医学研究

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水素酸素のメカニズム
主な器官系疾患
統合生物医療研究部門
文献
Research Projects
Cooperating Hospitals
Professional Academician
Indication
Various Patient Videos
Healing Crisis
Publication

水素酸素のメカニズム

水素分子は、ヒドロキシルラジカル(•OH)や過酸化亜硝酸陰イオン(ONOO⁻)などの活性酸素種(ROS)を中和する選択的抗酸化物質として作用し、酸化還元反応を通じてそれらを無害な水分子に変換します。

有害なフリーラジカルが除去された後、細胞の生存率および生理的恒常性が回復される可能性があります。細胞機能の改善は、さまざまな器官系の回復を支援することが示されており、時間の経過とともに臨床的な生化学マーカーにおいて進行的な改善が観察されます。

ヒト吸入において生理学的に許容される酸素濃度は、通常20%から40%の範囲になります。40%を超える酸素濃度に24時間以上曝露されると、酸素中毒により健康リスクを引き起こす可能性があります。アスクレピオスメディテックの水素酸素ネブライザーは、酸素濃度33%を含むガス混合物を供給するよう設計されており、長期吸入において医学的に認められた安全範囲内に十分収まっています。
水素酸素療法の主な生物学的特性
選択的抗酸化作用 – 水素は、有害な活性酸素種、特にヒドロキシルラジカル(•OH)を選択的に中和し、一酸化窒素(NO•)などの有益なシグナル伝達分子は保持します。
酸素利用の向上 – 水素(H₂)は、酸素(O₂)の細胞内取り込みと効率を改善し、組織の低酸素状態を緩和し、代謝回復を支援します。
抗炎症調節 – 水素は、NF-κBやNLRP3などの炎症誘発性シグナル伝達経路を抑制し、IL-6やTNF-αなどのサイトカインの発現を低下させます。
全身的な多臓器への効果 – 全身性吸収を通じて、水素酸素は肺、脳、心臓、腎臓をはじめとする複数の臓器における機能的な回復を支援します。
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主な器官系疾患

呼吸器系

呼吸器系

慢性閉塞性肺疾患(COPD)
大気汚染による肺損傷(例:PM2.5曝露)
肺線維症
急性肺損傷/急性呼吸促迫症候群(ALI/ARDS)
肺炎
ぜんそく
人工呼吸器による肺損傷
腫瘍学

腫瘍学

肝細胞がん
肺がん
大腸がん
胃がん
膠芽細胞腫
膵臓がん
乳がん
神経疾患

神経疾患

虚血性脳梗塞
脊髄損傷
新生児低酸素性虚血性脳症
パーキンソン病 アルツハイマー病
外傷性脳損傷 (TBI)
くも膜下出血
認識機能障害
筋骨格系

筋骨格系

変形性関節症
関節リウマチ
筋肉損傷
骨折回復
心臓血管系

心臓血管系

心筋虚血再かん流傷害
心不全
高血圧
心停止/心肺蘇生
血管性認知症
アテローム性動脈硬化
腎臓系

腎臓系

急性腎傷害 (AKI)
慢性腎疾患 (CKD)
腎虚血再かん流傷害
糖尿病性ネフロパシー
感染症と免疫疾患

感染症と免疫疾患

敗血症
全身性炎症反応症候群 (SIRS)
自己免疫疾患(一般分類)
移植片対宿主病 (GVHD)
Focused on H2-O2 medicine, Asclepius has conducted 300+ studies, 30 clinical trials (16 single/14 multi-center), published 90 papers, and secured 458 patents with China's top hospitals (to 2024).
As of December 1, 2024
Single Center Clinical Trials

Single Center Clinical Trials

Multi Center Clinical Trials

Multi Center Clinical Trials

Natural Clinical Program

Natural Clinical Program

Cooperating Hospitals

Anhui University of Chinese Medicine

Anhui University of Chinese Medicine

Beijing Anzhen Hospital, Capital Medical University

Beijing Anzhen Hospital, Capital Medical University

Beijing Chao-Yang Hospital, Capital Medical University

Beijing Chao-Yang Hospital, Capital Medical University

Tianjin Medical University General Hospital

Tianjin Medical University General Hospital

Shanghai Sixth People's Hospital

Shanghai Sixth People's Hospital

Guangzhou Fuda Cancer Hospital

Guangzhou Fuda Cancer Hospital

Guangdong Provincial People's Hospital

Guangdong Provincial People's Hospital

Shanghai Armed Police Corps Hospital

Shanghai Armed Police Corps Hospital

Anhui University of Chinese Medicine

Anhui University of Chinese Medicine

Beijing Anzhen Hospital, Capital Medical University

Beijing Anzhen Hospital, Capital Medical University

Beijing Chao-Yang Hospital, Capital Medical University

Beijing Chao-Yang Hospital, Capital Medical University

Tianjin Medical University General Hospital

Tianjin Medical University General Hospital

Shanghai Sixth People's Hospital

Shanghai Sixth People's Hospital

Guangzhou Fuda Cancer Hospital

Guangzhou Fuda Cancer Hospital

Guangdong Provincial People's Hospital

Guangdong Provincial People's Hospital

Shanghai Armed Police Corps Hospital

Shanghai Armed Police Corps Hospital

Academician's Professional Field

Academician 1

Academician 1

  • Hydrogen Tech Division: Electrolysis/nebulization engineers
  • Medical Applications: Pulmonologists & clinical researchers
Academician 2

Academician 2

  • Trial design team (FDA/NMPA compliance experts)
  • Hospital partnership managers
Academician 3

Academician 3

  • Medical device manufacturing specialists
  • SO 13485-certified quality control
Academician 4

Academician 4

  • Regulatory affairs (CE/FDA submissions)
  • 50-country distribution network
Indications by Week, Season, And Year

Indications by Week, Season, And Year

Short-term

(1-7days)
  • Sleep disorders
  • Alergic rhinitis
  • Respiratory disorders
  • Side effects of cancer treatment
  • Elderly with multiple comorbidities

Mid-term

(1-6 months)
  • Pulmonary nodules
  • COPD
  • Bronchitis
  • Asthma
  • Diabetic complications
  • Cancer
  • Depression

Long-term

(3-12 months)
  • Parkinson's
  • Alzheimer'S Post-stroke sequelae
  • Hypertension
  • Hyperlipidemia
  • Atherosclerosis
  • Hyperuricemia

Various Patient Videos

Effect of hydrogen on nitric oxide and its synthase in...
play

Effect of hydrogen on nitric oxide and its synthase in...

Consumption of hydrogen-rich water alleviates renal injury in...
play

Consumption of hydrogen-rich water alleviates renal injury in...

Dose-dependent inhibition of gastric injury by hydrogen in...
play

Dose-dependent inhibition of gastric injury by hydrogen in...

Effect of hydrogen on nitric oxide and its synthase in...
play

Effect of hydrogen on nitric oxide and its synthase in...

Healing Crisis

“My father has suffered from pulmonary fibrosis for many years. After using the hydrogen-oxygen nebulizer for three months, his physical condition has gradually improved and he can now go downstairs for a walk by himself.”
“My father has suffered from pulmonary fibrosis for many years. After using the hydrogen-oxygen nebulizer for three months, his physical condition has gradually improved and he can now go downstairs for a walk by himself.”
“My father has suffered from pulmonary fibrosis for many years. After using the hydrogen-oxygen nebulizer for three months, his physical condition has gradually improved and he can now go downstairs for a walk by himself.”

Scientific Papers & Hydrogen Cancer Control COVID-19

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