Why is it especially important for the elderly to inhale hydrogen-oxygen?

Aging brings reduced disease resistance and poorer recovery ability to the elderly.As the body ages,the incidence of most diseases increases exponentially—the elderly are more susceptible to illness than the young,their symptoms are more severe,their recovery efficiency is lower,and their recovery cycle is longer.In hydrogen-oxygen medical research,including recovery from radiotherapy and chemotherapy for malignant tumors,cardiovascular diseases,diabetes,Alzheimer's disease,Parkinson's disease,postoperative delirium in the elderly,age-related macular degeneration,gout,fatty liver disease,etc.,most clinical study participants are elderly patients.The results of these studies precisely indicate that hydrogen-oxygen holds significant value for improving age-related diseases and aiding in elderly recovery.

Aging is also a form of inflammation

Over the past twelve years,international research papers on hydrogen-oxygen medicine have fully demonstrated the mechanisms of hydrogen-oxygen in combating inflammation and oxidation.An article published in the internationally authoritative journal Nature Aging points out:aging itself is also a form of inflammation.Using hydrogen-oxygen to combat inflammation as a means to counteract natural aging may be a"prescription"for targeted treatment and maintaining health.[1]

In this experiment,the research team enrolled 1,001 participants aged between 8 and 96 years old,aiming to analyze how chronic,systemic inflammation changes with age by measuring multiple indicators of the immune system(such as gene expression and antibody cell counts).

Research indicates that the human immune system plays a significant role in the aging process.Simply put,as a person ages,they continuously experience cycles of falling ill,recovering,falling ill again,and recovering again.This repeated cycle leads to cellular damage and the release of inflammatory molecules,which in turn cause further wear and tear on tissues and organs.Consequently,the older one gets,the greater the"wear and tear,"making health more susceptible to severe impacts from diseases.

As a safe anti-inflammatory gas with no known side effects,hydrogen-oxygen is suitable for long-term use by middle-aged and elderly individuals.It has the potential to break the"spiral"of mutual reinforcement between aging and inflammation through its anti-inflammatory effects.Thus,it is not difficult to understand why,when elderly individuals with weaker constitutions suffer from malignant diseases and lack gentle yet effective treatment options,hydrogen-oxygen inhalation therapy recommended by doctors can yield unexpectedly positive results.

Research on Anti-Aging Effects of Hydrogen-Oxygen Therapy

In 2019,scientists used fruit flies to study the anti-aging effects of hydrogen molecule intake.The results showed that starting from the fourth day,the survival rate of fruit flies that ingested hydrogen molecules(hydrogen group)significantly exceeded that of ordinary fruit flies(control group).Fruit flies with a female gene defect(SOD)exhibited even better life-extending effects.[2]

In 2016,scientists discovered that hydrogen molecules can combat endothelial cell aging.Since endothelial cells are crucial functional cells in blood vessels,their aging leads to various vascular diseases,which in turn trigger common cardiovascular and cerebrovascular diseases in the elderly,thereby accelerating overall bodily aging.As the old saying goes,"Aging begins with the blood vessels."Inhaling hydrogen-oxygen to protect blood vessels may be an important method for human anti-aging.[3]

The body becomes deficient in hydrogen when ill:

In 2022,European scientists unexpectedly discovered that COVID-19 leads to a reduction in hydrogen-producing bacteria in the human body,and the cytokine storm also excessively consumes hydrogen molecules in patients.The combined result of these two factors is a significant decrease in hydrogen levels in patients'bodies.Conversely,clinical studies in China on improving COVID-19 symptoms by inhaling hydrogen-oxygen mixtures indicate that supplementing with hydrogen-oxygen is beneficial for patients'health,suggesting a positive correlation between the amount of hydrogen-oxygen and health.[4]

Longevity Correlates with High Hydrogen Levels:

A Japanese report found that centenarians possess a remarkably strong ability to produce hydrogen,reaching 59.4±62.6 ppm,which is over three times the level of ordinary healthy individuals.Even more unexpectedly,the descendants of these elderly individuals also exhibit a strong hydrogen-producing capacity,reaching 37.8±27.2 ppm.We often hear that the secrets of"longevity families"may lie in longevity genes,healthy dietary habits,etc.However,from this study,it appears that having a robust hydrogen-producing microbiota in the body,capable of generating large amounts of hydrogen for its own use,helps the body combat inflammation over the long term,which is the reason for being hydrogen-rich and long-lived.[5]


Hydrogen-Oxygen vs.Age-Related Diseases

Hydrogen-Oxygen vs.Atherosclerosis:Hydrogen-oxygen inhalation can reduce plaque formation and pathological changes in blood lipids,improve the function of high-density lipoprotein,reduce the level of oxidized low-density lipoprotein,decrease plaque formation,and enhance the stability of existing plaques.

Hydrogen-Oxygen vs.COPD:Hydrogen-oxygen inhalation improves symptoms in COPD patients through its anti-inflammatory,antioxidant,and oxygen-carrying diffusion effects.High-concentration hydrogen-oxygen inhalation suppresses serum and pulmonary levels of MDA,TNF-α,and IL-1β,"treating both the symptoms and the root cause."

Hydrogen-Oxygen vs.Age-Related Macular Degeneration,Dry Eye Disease,Retinal Damage,etc.:Hydrogen-oxygen inhalation downregulates vascular endothelial growth factor and hypoxia-inducible factor-1A,inhibits TNF-αand IL-6 to improve choroidal neovascularization caused by chronic light damage,suppresses vascular rupture and blood leakage,and hydrogen can also help keep the eyes moist.

Hydrogen-Oxygen Brain Protection:Non-small cell lung cancer tends to metastasize to the brain,a process involving multiple signaling pathways.In 2016,scientists demonstrated that hydrogen-oxygen can inhibit the aberrant activation of the WNT/β-CATENIN signaling pathway and also proved that hydrogen-oxygen can suppress SIRT1 signaling in different models.

Hydrogen-Oxygen Vascular Protection:Hydrogen-oxygen scavenges free radicals,exerts antioxidant effects,and inhibits lipid peroxidation,thereby suppressing oxidative damage to brain cells,vascular endothelial cells,and nerve cells.

Hydrogen-Oxygen vs.Gout:Hydrogen-oxygen inhalation has a good protective effect on the kidneys,and enhanced renal function is beneficial for the excretion of uric acid.Additionally,the anti-inflammatory and antioxidant effects of hydrogen-oxygen inhalation fundamentally correct disordered cellular states,gradually alleviating the root cause of purine metabolism disorders.

Hydrogen-Oxygen vs.Parkinson's:Gut microbiota can produce hydrogen,which has antioxidant,anti-apoptotic,anti-inflammatory,and cytoprotective effects;a reduction in hydrogen produced by gut microbiota may play a role in the pathogenesis of Parkinson's disease,and hydrogen supplementation could be an effective therapy for Parkinson's disease.

Hydrogen-Oxygen vs.Sleep Issues in the Elderly:Hydrogen-oxygen inhalation reduces sympathetic nerve activity and enhances parasympathetic nerve activity,making it easier to fall asleep and promoting deeper sleep.

Hydrogen-Oxygen vs.Postoperative Delirium in the Elderly:During the PACU(Postanesthesia Care Unit)period,all patients undergoing thoracic surgery experienced hypoxemia,while the incidence of other adverse reactions was essentially the same.No significant differences were found in the postoperative hospital stay or sleep quality on postoperative days 1,3,and 7.The postoperative C-reactive protein levels in the hydrogen-oxygen group were significantly lower than those in the control group,and the incidence of delirium in the hydrogen-oxygen group was substantially reduced!

Hydrogen-Oxygen vs.White Lung in Elderly COVID-19 Patients:Hydrogen-oxygen combats the damage caused by the COVID-19 virus through anti-inflammatory and antioxidant effects,improving patient condition by enhancing oxygen diffusion.Famous"Beating the Gong to Save Mother"case report details the entire process of a COVID-19 patient's recovery from"white lung"to gradual improvement.

Hydrogen-Oxygen vs.Arthritis:Hydrogen-oxygen inhalation alleviates mechanical hyperalgesia and oxidative stress in arthritis,and reduces joint tissue damage.

Hydrogen-Oxygen vs.Pressure Ulcers in Elderly Patients:Inhalation of hydrogen-oxygen mixed gas has a protective effect against pressure ulcers.Hydrogen-oxygen mixed gas therapy can significantly reduce wound area,accelerate skin ulcer recovery,improve oxidative DNA damage,and reduce inflammation.

Hydrogen-Oxygen vs.Alzheimer's Disease:Hydrogen-oxygen inhalation participates in Sirt1-FoxO3a axis signaling,improves gut microbiota to enhance the brain-gut axis,boosts immunity,and thereby plays a role in improving and preventing Alzheimer's disease.

Hydrogen-Oxygen vs.Cancer:The occurrence of tumors is closely related to inflammation and oxidative stress.Hydrogen-oxygen inhalation is one of the most effective tools for humans to combat inflammation and oxidative stress.Hydrogen-oxygen has shown inhibitory effects on various types of tumors.

Over the past twelve years,there has been extensive research on hydrogen-oxygen for various chronic and malignant diseases.The above is just the tip of the iceberg.For elderly individuals with compromised immunity,hydrogen-oxygen inhalation is not only a means to ameliorate diseases,but its characteristic of having no side effects also determines that long-term use of hydrogen-oxygen will be an important choice for the elderly in disease prevention.·Building upon the above research,future hydrogen-oxygen medicine will present more research findings,further integrating into the health lives of the elderly population.

References:

[1]Sayed,N.,Huang,Y.,Nguyen,K.et al.An inflammatory aging clock(iAge)based on deep learning tracks multimorbidity,immunosenescence,frailty and cardiovascular aging.Nat Aging 1,598–615(2021).

[2]Chung-Hsing Chao.Hydrogen Water on Survival Rate after Fasting in Drosophila Model.Chapter In“Superoxide Dismutase”,2019.Publisher:IntechOpen

[3]Hara F,Tatebe J,Watanabe I,etal.Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells.[J].Circulation Journal Official Journal of the Japanese Circulation Society,2016,80(9):2037.

[4]Ostojic SM(2022)Malproduction of endogenous hydrogen gas in COVID-19.Front.Cell.Infect.Microbiol.12:924832.doi:10.3389/fcimb.2022.924832

[5]Increased Concentrations of BreathHydrogen Gas in Japanese Centenarians